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The m.11778 A > G variant associated with the coexistence of Leber's hereditary optic neuropathy and multiple sclerosis-like illness dysregulates the metabolic interplay between mitochondrial oxidative phosphorylation and glycolysis.

Uittenbogaard M1, Brantner CA2, Fang Z3, Wong LJ3, Gropman A4, Chiaramello A5

aAstract.